A man has been left with serious leg injuries after a break-in at Dudley over the weekend.

Police say four people forced their way into a home on Tumut Street around 4.00am on Saturday and attempted to steal a motorbike.

They were confronted by neighbours and following a struggle, fled in a vehicle, striking a 42-year-old man.

He was taken to the John Hunter Hospital in a serious but stable condition.

Police say the four culprits were males aged between 15 and 20 who fled in a turquoise-coloured Volkswagen T-Cross.